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Lantheus Holdings Inc

99.96+89.7%1Y · USD

Lantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products for heart disease, cancer, and other conditions worldwide. Its offerings include DEFINITY, TechneLite, Xenon-133, Neurolite, Cardiolite, and PYLARIFY, along with software such as the Automated Bone Scan Index, aPROMISE, and PYLARIFY AI, and RELISTOR for opioid-induced constipation. The company also develops therapies and imaging agents including PNT2002, PNT2003, MK-6240, LNTH-2401, LNTH-2402, LNTH-2403, LNTH-2404, LNTH-250, LNTH-2515, and LNTH-1363S. Founded in 1956, it is based in Bedford, Massachusetts, and has collaboration agreements with GE Healthcare, Curium Pharma, POINT, Regeneron, and Ratio Therapeutics LLC.

Price · split & dividend adjusted

Why is Lantheus Holdings Inc (LNTH) moving?

Latest
▲2▼1

Curium's $8B buyout and new FDA approval reshape Lantheus

  • Curium agrees to acquire Lantheus for up to $8 billion Curium will pay $102.50 per share in cash plus up to $12 more if sales targets are met, a 14.9% premium. This puts a firm floor under the stock and is the main reason it trades near the offer price.

    The buyout is the single biggest force driving LNTH's price and future value.

  • FDA approves Tauklarify for tau PET imaging The FDA approved Tauklarify, a new imaging agent for Alzheimer's tau pathology. This adds a new product to Lantheus's portfolio and could support the contingent value rights tied to future sales.

    A new FDA approval is a fresh positive catalyst that can affect the buyout's contingent payments.

  • FDA rejects LNTH-2501 due to third-party facility issues The FDA issued a Complete Response Letter for LNTH-2501, a PET diagnostic for neuroendocrine tumors, because of unresolved manufacturing issues at a partner's facility. This delays a potential product but does not question the drug's data.

    This is a fresh regulatory setback that could weigh on sentiment and future growth prospects.

Q3 2026
▲2▼1

Curium's $8B buyout and new FDA approval reshape Lantheus

  • Curium agrees to acquire Lantheus for up to $8 billion Curium will pay $102.50 per share in cash plus up to $12 more if sales targets are met, a 14.9% premium. This puts a firm floor under the stock and is the main reason it trades near the offer price.

    The buyout is the single biggest force driving LNTH's price and future value.

  • FDA approves Tauklarify for tau PET imaging The FDA approved Tauklarify, a new imaging agent for Alzheimer's tau pathology. This adds a new product to Lantheus's portfolio and could support the contingent value rights tied to future sales.

    A new FDA approval is a fresh positive catalyst that can affect the buyout's contingent payments.

  • FDA rejects LNTH-2501 due to third-party facility issues The FDA issued a Complete Response Letter for LNTH-2501, a PET diagnostic for neuroendocrine tumors, because of unresolved manufacturing issues at a partner's facility. This delays a potential product but does not question the drug's data.

    This is a fresh regulatory setback that could weigh on sentiment and future growth prospects.

News & notes moving LNTH
United States
Biotech & Genomic Medicine▲

Polaris Flags Lantheus Rally on Earnings, FDA Approval, $7 Billion Curium Bid

Polaris Capital Management's Global Equity Strategy highlighted Lantheus Holdings in its second-quarter 2026 investor letter, citing strong quarterly earnings, the FDA approval of PYLARIFY TruVu, and intensified M&A interest from a potential $7 billion takeover bid by PE-backed Curium Pharma. The Polaris Global Equity Composite returned 13.26% net of fees for the quarter, trailing the MSCI World Index's 13.90% return with gross dividends reinvested, but remained ahead year-to-date through June 30, 2026, gaining 19.95% versus 9.94% for the benchmark. Lantheus closed at $100.28 per share on September 22, 2026, down 0.58% over the past month but up 92.62% over the past 52 weeks, with a market capitalization of $6.55 billion and a 52-week range of $49.67 to $111.86. Forty hedge fund portfolios held Lantheus at the end of the second quarter, up from 31 in the previous quarter.
About megatrends
Biotech & Genomic Medicine › Diagnostics & Precision Testing ▲Regulation
LNTH · Capital · Positive Strong quarterly earnings, FDA approval of PYLARIFY TruVu, and a $7 billion takeover bid from Curium all cited as drivers of the rally.
Polaris Capital Management · · Neutral Polaris is the letter's author, mentioned only for its fund performance, not a company-specific development.
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United States
LNTH

Lantheus Withdraws and Refiles HSR Filing for $8B Curium Acquisition

Lantheus Holdings said it has withdrawn and refiled its Hart-Scott-Rodino Act pre-merger notification regarding its $8B acquisition of Curium. The withdrawal, done on Sept. 17, was made to provide the Federal Trade Commission with additional time to review the merger, according to an SEC filing. The resubmission was filed on Monday, meaning the standard HSR 30-day waiting period will end on Oct. 21 at 11:59 p.m. Lantheus said a refiling is routine procedure for antitrust review and still expects the merger to close in H1 2027.
LNTH · Regulation · Neutral Lantheus withdrew and refiled its HSR pre-merger notification for the $8B Curium acquisition to give the FTC more review time, a routine antitrust step that delays but does not block the deal.
Curium · Regulation · Neutral Curium is the target of Lantheus's $8B acquisition, whose HSR filing was withdrawn and refiled for extended FTC antitrust review, still expected to close in H1 2027.
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United States
Biotech & Genomic Medicine▲

Lantheus wins FDA approval for Tauklarify tau PET imaging agent

Lantheus Holdings announced on Friday that the FDA has approved Tauklarify, a radiodiagnostic agent for detecting tau pathology in the brain of adults with Alzheimer’s disease using positron emission tomography. The approval covers use in cognitively impaired adults being evaluated for Alzheimer’s to determine whether tau neurofibrillary tangle pathology is present. The company said tau PET imaging complements amyloid PET and other diagnostic tools, and the approval is supported by data from two studies involving more than 500 patients who received a single intravenous dose. Lantheus CEO Mary Anne noted that clinicians are seeking a more complete understanding of the disease as the field advances.
About megatrends
Biotech & Genomic Medicine › Tools, Diagnostics & CDMO ▲Demand
LNTH · Regulation · Positive FDA approval of Tauklarify for tau PET imaging is a regulatory win for Lantheus.
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Global
Artificial Intelligence▲impact 4

Key M&A deals this week include DoubleVerify, AMD, Visa, Prologis

Several major acquisition agreements were announced this week. DoubleVerify agreed to be acquired by Nielsen in an all-cash transaction valued at approximately $2.15 billion, with shareholders receiving $13.60 per share. Advanced Micro Devices signed a definitive agreement to acquire Taalas, a developer of specialized AI inference silicon. Visa agreed to acquire BioCatch, a provider of behavioral-first fraud intelligence, for $2.4 billion from funds advised by Permira. Prologis reached an agreement to buy SEGRO plc for about $18.8 billion after securing a board recommendation. Bending Spoons is acquiring Airtable in an all-cash transaction valuing the workflow software company at an enterprise value of $1.285 billion, implying an equity value of about $2.25 billion. Curium announced a deal to acquire all outstanding shares of Lantheus Holdings for up to $114.50 per share in cash, including contingent value rights. Atkore entered into a definitive agreement to be acquired by Prysmian in an all-cash transaction representing an enterprise value of approximately $3.8 billion. Supernus Pharmaceuticals and Indivior Pharmaceuticals agreed to merge in an all-stock merger of equals. Digital Brands Group shares surged after receiving a proposal from an existing shareholder to acquire all outstanding shares for $77.58 per share in cash. Gloo entered into a definitive agreement to acquire Cedarstone, a business services firm serving nonprofit organizations.
About megatrends
Artificial Intelligence › Inference-Optimized Silicon ▲Technology
Digital Finance & Tokenization › Payments Modernization & Rails ▲Technology
Semiconductors › Logic, Compute & Connectivity Processors Competition
Cloud & Digital Infrastructure › Hyperscale Cloud (IaaS / PaaS) Competition
Cloud & Digital Infrastructure › Data Platforms & Analytics Competition
ATKR · Capital · Positive Atkore to be acquired by Prysmian in an all-cash deal at $3.8 billion enterprise value.
DBGI · Capital · Positive Digital Brands Group receives acquisition proposal at $77.58 per share in cash.
DV · Capital · Positive DoubleVerify to be acquired by Nielsen for $13.60 per share in cash.
GLOO · Capital · Positive Gloo acquires Cedarstone, a business services firm, expanding its operations.
LNTH · Capital · Positive Curium to acquire all shares for up to $114.50 cash
PLD · Capital · Positive Agreement to buy SEGRO plc for $18.8 billion
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LNTH

Halper Sadeh LLC Investigates MKTX, SMTI, LNTH Deals for Shareholder Fairness

Halper Sadeh LLC, an investor rights law firm, is investigating whether MarketAxess Holdings, Sanara MedTech, and Lantheus Holdings are obtaining fair deals for their shareholders in proposed acquisitions. The firm is examining MarketAxess Holdings' sale to Intercontinental Exchange for $167.00 per share in cash, Sanara MedTech's sale to MiMedx Group for $33.00 in cash and 0.4735 shares of MiMedx common stock per Sanara share, and Lantheus Holdings' sale to Curium US Holdings for $102.50 per share in cash plus non-transferable Contingent Value Rights providing up to $12.00 per share in potential additional cash payments tied to commercial milestones through 2030. Halper Sadeh LLC may seek increased consideration, additional disclosures, or other relief on behalf of shareholders, and encourages affected investors to contact the firm at no cost to discuss their legal rights and options.
LNTH · Capital · Neutral Investigation into fairness of acquisition deal for shareholders
MKTX · Capital · Neutral Investigation into fairness of acquisition deal for shareholders
SMTI · Capital · Neutral Investigation into fairness of acquisition deal for shareholders
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Biotech & Genomic Medicine▲2impact 4

Curium to acquire Lantheus in all-cash deal worth up to $8 billion

CapVest Partners-backed Curium has agreed to buy rival US-based radiopharmaceutical company Lantheus in an all-cash deal worth up to nearly $8 billion. Under the agreement, Curium US will purchase all outstanding shares of Lantheus for $102.50 per share upon closing, with shareholders also set to receive non-transferable contingent value rights that could provide up to an additional $12.00 per share if certain commercial milestones are met by 2030, bringing the potential total consideration per share to $114.50. The offer represents a 38% premium to Lantheus' 60-day volume-weighted average price and a 21% premium above its closing price as of 21 May 2026, the last day before media reports emerged about the potential sale. The proposed transaction has received unanimous approval from Lantheus' Board of Directors and is expected to close in the first half of 2027, subject to regulatory and shareholder approvals, with financing through a mix of debt and equity and no financial conditions attached.
About megatrends
Biotech & Genomic Medicine › Oncology Therapeutics Competition
LNTH · Capital · Positive Acquired by Curium at a 38% premium to 60-day VWAP, with potential additional CVRs.
Curium · Capital · Positive Expands Curium's radiopharmaceutical portfolio through acquisition of Lantheus.
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LNTH

Halper Sadeh LLC Investigates Lantheus, Atkore, and Indivior Deals for Shareholder Fairness

Halper Sadeh LLC, an investor rights law firm, is investigating whether the proposed sales of Lantheus Holdings, Atkore, and Indivior Pharmaceuticals are obtaining fair deals for their shareholders. The firm is examining Lantheus Holdings' sale to Curium US Holdings for $102.50 per share in cash plus non-transferable Contingent Value Rights providing up to $12.00 per share in potential additional cash payments, Atkore's sale to Prysmian for $95.00 per share in cash, and Indivior's merger with Supernus Pharmaceuticals in which Indivior shareholders would own approximately 56.5% of the combined company. Halper Sadeh LLC may seek increased consideration, additional disclosures, or other relief on behalf of shareholders, and encourages them to contact the firm to discuss their rights at no cost.
ATKR · Capital · Neutral Investigation into whether Atkore's sale to Prysmian at $95.00 per share is fair to shareholders; may seek increased consideration.
INDV · Capital · Neutral Investigation into Indivior's merger with Supernus, where shareholders would own 56.5% of combined company; may seek better terms.
LNTH · Capital · Neutral Investigation into Lantheus's sale to Curium for $102.50 per share plus CVRs; may seek increased consideration or disclosures.
0NUX.LSE · Capital · Neutral Atkore's sale to Prysmian is under investigation; Prysmian is the acquirer, potential impact on deal terms.
SUPN · Capital · Neutral Indivior's merger with Supernus is under investigation; Supernus is the acquirer, potential impact on deal terms.
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Biotech & Genomic Medicine▲impact 4

KKR nears Integer Holdings buyout, ICE to acquire MarketAxess in $6 billion deal

Several major deals were reported this week across sectors. KKR is close to a deal to take medical-device outsourcer Integer Holdings private, sending its shares up 20%. Intercontinental Exchange agreed to acquire fixed-income electronic trading platform MarketAxess Holdings in a transaction valuing its equity at roughly $6.0 billion and total enterprise at $5.7 billion. Grant Thornton Advisors agreed to buy professional services firm CBIZ in an all-cash deal with a $5 billion enterprise value, backed by New Mountain Capital. Koch Inc. is exploring a sale of data center developer Edged that could value it at more than $15 billion. KKR and Energy Capital Partners agreed to acquire Ireland-based energy distributor DCC Energy in a deal valued at about £5.7 billion, with shareholders receiving £65.25 per share in cash plus a final dividend and a potential contingent payment. TransDigm Group agreed to acquire Prince & Izant from Industrial Growth Partners for approximately $1.066 billion in cash. argenx SE will acquire Forte Biosciences for $77 per share in cash, a transaction valued at roughly $2.2 billion, adding a first-in-class anti-CD122 antibody to its immunology portfolio. Ambarella shares surged 19% on a report that NXP Semiconductors is in talks to acquire the chip designer, though a deal is not certain. Curium is in advanced talks to buy radiopharma company Lantheus Holdings for about $102 per share upfront plus $12.50 per share in contingent value rights.
About megatrends
Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics ▲Competition
Semiconductors › Logic, Compute & Connectivity Processors Competition
Defense & Geopolitical Fragmentation › Defense Electronics, EW & Sensors Competition
MKTX · Capital · Positive ICE agreed to acquire MarketAxess in a $6 billion deal, valuing its equity at $6.0 billion.
AMBA · Capital · Positive NXP Semiconductors is in talks to acquire Ambarella, driving shares up 19%.
CBZ · Capital · Positive Grant Thornton Advisors agreed to buy CBIZ in an all-cash deal with a $5 billion enterprise value.
DCC.LSE · Capital · Positive KKR and Energy Capital Partners agree to acquire DCC Energy at £65.25 per share cash plus dividend.
FBRX · Capital · Positive argenx will acquire Forte Biosciences for $77 per share in cash, a $2.2 billion deal.
ICE · Capital · Positive Intercontinental Exchange agreed to acquire MarketAxess in a $6 billion deal.
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Biotech & Genomic Medicine▲impact 4

Bristol-Myers Raises Full-Year Outlook as Cancer Drugs Drive Q2 Beat

Bristol-Myers Squibb lifted its full-year outlook after reporting better-than-expected second-quarter 2026 results driven by higher sales of its cancer therapies. The company posted approximately $13.0 billion in revenue, beating consensus by $1.23 billion, with its growth portfolio contributing $7.6 billion. Adjusted earnings per share rose about 40% year-over-year to $2.04, exceeding estimates by $0.44. Bristol-Myers now expects full-year revenue of about $49.0 billion to $50.0 billion and adjusted EPS of $6.75 to $7.00, up from prior guidance and ahead of consensus. In other healthcare news, Johnson & Johnson agreed to pay up to $5.5 billion to settle remaining talc lawsuits alleging its products caused ovarian cancer, conditioned on at least 95% participation by claimants. Curium is in advanced talks to acquire Lantheus Holdings for about $7 billion upfront, with an additional $12.50 per share in contingent value rights, potentially valuing the deal at $8 billion. Boston Scientific shares slipped after its full-year outlook trailed consensus, despite second-quarter revenue of $5.4 billion beating estimates. Most Medicare Part D enrollees will face higher premiums in 2027 after the Trump administration ended a subsidy program, with three out of four seeing increases. The S&P 500 Health Care Index Sector edged up 0.12% during the week.
About megatrends
Biotech & Genomic Medicine › Oncology Therapeutics ▲Demand
Aging Population › Chronic-Disease Pharma Franchises ▲Demand
BMY · Capital · Positive Q2 beat and raised full-year guidance
BSX · Capital · Negative Full-year outlook trailed consensus despite revenue beat
JNJ · Regulation · Positive Agreed to settle talc lawsuits for up to $5.5B
LNTH · Capital · Positive Curium in talks to acquire Lantheus for ~$7B upfront plus CVRs
Curium · Capital · Positive Curium in advanced talks to acquire Lantheus
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LNTH▼3

Lantheus receives FDA Complete Response Letter for LNTH-2501

Lantheus has received a Complete Response Letter from the US Food and Drug Administration for LNTH-2501, its PET diagnostic imaging kit targeting somatostatin receptor-positive neuroendocrine tumors. The agency indicated the application cannot be approved due to ongoing issues at a third-party manufacturing site, though no issues were noted with the data supporting LNTH-2501. Lantheus CEO Mary Anne Heino stated the company is working closely with its partner and the FDA to address the facility manufacturing-related conditions and advance the program.
LNTH · Regulation · Negative FDA Complete Response Letter delays approval of LNTH-2501 due to third-party manufacturing issues.
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LNTH

Healthcare Equipment and Supplies Stocks Post Mixed Q1 Results

Healthcare equipment and supplies stocks reported mixed first-quarter results, with the 37 companies tracked collectively beating revenue estimates by 2.3% but issuing next-quarter guidance 1.3% below expectations. Lantheus posted revenues of $377.3 million, up 1.2% year on year and exceeding estimates by 6.4%, though its full-year revenue guidance missed. STAAR Surgical delivered the strongest performance, with revenues surging 120% to $93.52 million and beating estimates by 20.8%, while Stryker was the weakest, reporting $6.02 billion in revenue that fell 5% short of expectations. Abbott Laboratories reported $11.16 billion in revenue, up 7.8% and beating estimates by 1.3%, and Integra LifeSciences posted $391.9 million, up 2.4% and exceeding estimates by 2.6%. On average, share prices across the group have declined 1.4% since the latest earnings results.
STAA · Capital · Positive Revenue surged 120% and beat estimates by 20.8%, the strongest performance.
LNTH · Capital · Neutral Revenue beat estimates by 6.4% but full-year guidance missed.
SYK · Capital · Negative Revenue fell 5% short of expectations, the weakest in the group.
ABT · Capital · Positive Revenue beat estimates by 1.3% and grew 7.8% year on year.
IART · Capital · Positive Revenue exceeded estimates by 2.6% and grew 2.4% year on year.
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