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Atrium Therapeutics, Inc. Common Stock

Atrium Therapeutics, Inc. is a biopharmaceutical company focused on delivering RNA therapeutics to the heart to transform care for people with cardiomyopathies. Its development-stage product candidates include ATR 1072, an siRNA-based therapy targeting PRKAG2 for PRKAG2 syndrome, and ATR 1086, an siRNA-based therapy targeting PLN for PLN cardiomyopathy. The company also has a pipeline aimed at a range of genetic and cardiac diseases, and has research collaboration and license agreements with Bristol-Myers Squibb Company and Eli Lilly and Company. Incorporated in 2025, it is headquartered in San Diego, California.

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Biotech & Genomic Medicine▼

Atrium Therapeutics Advances Pipeline as Cash Burn Widens

Atrium Therapeutics reported second-quarter 2026 results that mixed real clinical progress with a familiar biotech question: how long the cash lasts. The company disclosed FDA clearance of its IND application for ATR 1072 and the launch of Corventis, its first Phase 1/2 trial and the first study anywhere testing a disease-modifying treatment for PRKAG2 syndrome. It also collected a second milestone payment from its cardiovascular partnership with Bristol Myers Squibb. None of that changes the fact that Atrium still spends far more than it brings in. Second-quarter collaboration revenue came in at $3 million, a fraction of the $15.3 million spent on research and development and the $10.3 million spent on general and administrative costs, a combined $25.6 million in expenses against a sliver of revenue. With $263.9 million in cash, cash equivalents, and short-term investments as of June 30, and that milestone payment included, the company says it can fund operations through mid-2028. Hedge fund ownership of Atrium fell from 37 funds to 30 heading into this report, a pullback that suggests some institutional money trimmed positions ahead of the clinical and financial update.
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Biotech & Genomic Medicine › Oncology Therapeutics Competition
RNA · Capital · Negative Q2 expenses of $25.6 million against just $3 million in collaboration revenue widen cash burn, though cash funds operations through mid-2028.
RNA · Technology · Neutral FDA clearance of the ATR 1072 IND and launch of the Corventis Phase 1/2 trial mark clinical progress.
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United States
Biotech & Genomic Medicine▲

Atrium Therapeutics Reports Second Quarter 2026 Financial Results

Atrium Therapeutics reported second quarter 2026 financial results and announced FDA clearance of its IND application for ATR 1072, enabling the launch of the Corventis Phase 1/2 trial in PRKAG2 syndrome. The company also earned a second milestone payment of $15 million under its global cardiovascular collaboration with Bristol Myers Squibb, which will be recorded in the third quarter. Collaboration revenue was $3.0 million for the quarter, while R&D expenses were $15.3 million and G&A expenses were $10.3 million. As of June 30, 2026, Atrium had $263.9 million in cash, cash equivalents and short-term investments, which the company believes is sufficient to fund operations through mid-2028. The Corventis trial is expected to enroll its first participant by the end of 2026, with initial proof-of-concept data anticipated in the second half of 2027.
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Biotech & Genomic Medicine › Cardiovascular & Heart-Failure Therapeutics ▲Regulation
RNA · Capital · Positive Reported Q2 2026 results with $263.9M cash funding operations through mid-2028 and a $15M BMS milestone payment.
RNA · Technology · Positive FDA clearance of its IND for ATR 1072 enables the Corventis Phase 1/2 trial in PRKAG2 syndrome.
BMY · Capital · Positive Atrium earned a $15M milestone payment under its collaboration with Bristol Myers Squibb, indicating progress in their partnership.
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RNA

Atrium Therapeutics awards inducement grants to eight new non-executive employees

Atrium Therapeutics announced it granted equity awards to eight newly hired non-executive employees as a material inducement to their employment. The awards, made under the company's 2026 Employment Inducement Incentive Award Plan, consist of non-qualified stock options to purchase an aggregate of 66,000 shares of common stock at an exercise price of $12.66 per share, and restricted stock units covering an aggregate of 33,000 shares. Both the options and restricted stock units vest 25% on the first anniversary of the grant date, with the remaining shares vesting monthly over 36 months for the options and annually over three years for the restricted stock units, subject to continued service. The grants were approved by the Human Capital Management Committee of the board of directors and were made outside the company's stockholder-approved equity plans in accordance with Nasdaq Listing Rule 5635(c)(4).
RNA · Capital · Neutral Equity grants to new hires are a routine capital event; no direct impact on company performance.
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