Pulmatrix, Inc. is a biopharmaceutical company focused on developing novel inhaled therapeutic products to prevent and treat migraine and respiratory diseases with unmet medical needs in the United States. The company offers iSPERSE, an engineered dry powder delivery platform that enables delivery of small or large molecule drugs to the lungs by inhalation for local or systemic applications. It is developing PUR1800, a narrow spectrum kinase inhibitor that completed Phase 1b clinical trials for acute exacerbations in chronic obstructive pulmonary disease; PUR1900 for allergic bronchopulmonary aspergillosis in patients with asthma and cystic fibrosis; and PUR3100, an iSPERSE formulation of dihydroergotamine in Phase 1 for acute migraine. It has a license agreement with RespiVert Ltd. for access to a portfolio of kinase inhibitor compounds. The company was founded in 2003 and is headquartered in Framingham, Massachusetts.