Collegium Pharmaceutical, Inc. is a specialty pharmaceutical company that develops and commercializes medicines for pain management. Its portfolio includes Jornay PM, a central nervous system stimulant containing methylphenidate HCl for attention deficit hyperactivity disorder; Belbuca, a buprenorphine buccal film for severe and persistent pain requiring extended treatment; Xtampza ER, an abuse-deterrent, extended-release oral formulation of oxycodone for severe pain requiring daily management; Nucynta ER and Nucynta IR, extended-release and immediate-release oral formulations of tapentadol for acute, severe, and persistent pain; and Symproic, an oral formulation of naldemedine for opioid-induced constipation in adults with chronic non-cancer pain. Formerly known as Collegium Pharmaceuticals, Inc., it changed its name to Collegium Pharmaceutical, Inc. in October 2003. The company was incorporated in 2002 and is headquartered in Stoughton, Massachusetts.