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Genflow Biosciences plc

Genflow Biosciences plc is a biotechnology company that, along with its subsidiaries, conducts research and development of gene therapies in the United Kingdom, Belgium, and the United States. Its pre-clinical stage drug candidates include GF-1002, an intravenously infused adeno-associated viral vector-based gene therapy for metabolic associated steatohepatitis; GF-1003, a topical delivery of SIRT6 to the skin; GF-1004, a non-human anti-aging pipeline for veterinary use; GF-1005 for mitochondrial dysfunction and sarcopenia; and GF-1006, an ophthalmology mRNA SIRT6 candidate for cornea pathologies and glaucoma. Founded in 2020, the company is headquartered in London, the United Kingdom.

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United KingdomMadagascarGreenland
Longevity & Life Extension▲

Genflow trial hits endpoint; 80 Mile agrees takeover

Genflow Biosciences announced that its SLAB gene therapy trial in ageing dogs has met its primary endpoint, and it is now in talks with major animal health companies about a licensing deal. EnergyPathways has appointed Jacobs as engineering and regulatory partner for its MESH energy storage project in the Irish Sea, moving toward a key Ofgem funding submission. Itaconix is targeting a doubling of revenue to $30 million in the medium term, after half-year revenue jumped 72% on strong detergent demand. Gaming Realms says it is well placed to keep growing despite a UK tax hike hitting margins, with core content licensing revenue up 12% in the first half. Total Graphite reports that fresh drilling in Madagascar has strengthened the case for restarting mining at Vatomina, with one hole returning 19 metres at 3.3% graphite. 80 Mile has agreed indicative terms for a £61.5 million all-share takeover by Nasdaq-listed Greenland Energy, representing a near-47% premium to its share price.
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Longevity & Life Extension › Cellular Reprogramming & Rejuvenation ▲Technology
Critical Materials & Supply Chain › Rare Earths & Permanent Magnets ▲Supply
80M.LSE · Capital · Positive Agreed to a £61.5m all-share takeover by Greenland Energy at a near-47% premium
GENF.LSE · Technology · Positive SLAB gene therapy trial in ageing dogs met its primary endpoint, prompting licensing talks with animal health companies
ITX.LSE · Demand · Positive Half-year revenue jumped 72% on strong detergent demand, targeting $30m medium-term revenue.
GLND · Capital · Positive Agreed indicative terms for a £61.5m all-share takeover of 80 Mile, an M&A event for the acquirer
GMR.LSE · Regulation · Neutral UK tax hike is hitting margins, though core content licensing revenue rose 12% in H1.
EPP.LSE · · Neutral Appointed Jacobs as engineering and regulatory partner for its MESH storage project, moving toward Ofgem funding submission
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Longevity & Life Extension▲

Animal Longevity Summit to hold first global scientific forum on healthy aging in animals

The Animal Longevity Summit has announced its inaugural two-day scientific conference, taking place October 1–2, 2026, in Toronto. The event will bring together leading experts in geroscience, veterinary medicine, biotechnology, and aging research to explore how the biology of aging can be measured, slowed, and translated into longer, healthier lives, beginning with animals. The summit arrives as landmark initiatives such as the Dog Aging Project and a growing number of veterinary clinical trials generate the first large-scale datasets on interventions to improve healthspan and longevity in companion animals. The conference program will feature eight scientific tracks covering canine longevity, comparative biology of aging, biomarkers, longevity interventions, veterinary geroscience, cross-species translation to human health, and emerging research from early-career scientists. The inaugural speaker lineup includes Dr. Matt Kaeberlein of the Dog Aging Project, Dr. Vera Gorbunova of the University of Rochester, Dr. Aubrey de Grey of the LEV Foundation, Dr. Varun Dwaraka of TruDiagnostic, Liz Parrish of BioViva, and Dr. Raghav Sehgal of Yale, with additional speakers to be announced. Industry participation is also expected, with Genflow Biosciences confirming it will present new findings from its SLAB study investigating gene therapy in aged beagles.
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Longevity & Life Extension › Longevity Diagnostics & Aging Clocks ▲Demand
Longevity & Life Extension › Metabolic Aging & Geroprotectors Technology
GENF.LSE · Demand · Positive Genflow will present new SLAB study findings at the summit, highlighting its gene therapy for aged beagles.
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GENF.LSE▲

Arrow Exploration brings Icaco-2 well on production at 830 barrels per day

Arrow Exploration Corp has brought its Icaco-2 well in Colombia on production at around 830 barrels per day gross, taking total corporate output to approximately 5,000 barrels of oil equivalent per day. CEO Marshall Abbott says the Icaco discovery may be material to Arrow, with horizontal and vertical development wells already planned. Frontier IP Group PLC has raised £4 million through a placing and subscription at 12p per share, with six directors participating in the subscription element, and a retail offer through BookBuild aims to raise a further £400,000 before closing at 5pm on 18 June. RC365 Holding PLC has signed a point-of-sale agreement with StarCruises International to deploy its RC3.0 payments platform across cruise operations in Asia, including cryptocurrency acceptance and multi-language support. Coiled Therapeutics has appointed two senior oncologists to a newly formed medical advisory board guiding its lead cancer drug AO-252 through phase I trials, with Professor Guru Sonpavde and Dr Alexander Spira shaping clinical strategy as the programme moves toward expansion cohorts in the second half of 2026. Genflow Biosciences Ltd has been invited to present results from its SLAB dog longevity study at the Animal Longevity Summit in Toronto in October, with the study evaluating its SIRT6 gene therapy in aged beagles concluding this month. Pan African Resources PLC will join the FTSE 250 from 23 June, following the court sanction of its all-share acquisition of Emmerson Resources, and also joins the FTSE 350, FTSE All-Share and related indices.
AXL.LSE · Supply · Positive Icaco-2 well brought on production at 830 bpd, boosting total output to ~5,000 boepd.
FIPP.LSE · Capital · Positive Raised £4 million via placing and subscription at 12p per share, with retail offer for additional £400,000.
GENF.LSE · Technology · Positive Invited to present SLAB dog longevity study results at Animal Longevity Summit, evaluating SIRT6 gene therapy.
PAF.LSE · Capital · Positive Will join FTSE 250 from 23 June after court sanction of Emmerson Resources acquisition.
RCGH.LSE · Demand · Positive Signed point-of-sale agreement with StarCruises to deploy RC3.0 payments platform across Asia cruise operations.
Coiled Therapeutics · Technology · Positive Appoints senior oncologists to medical advisory board guiding lead cancer drug AO-252 through phase I trials, with expansion cohorts planned.
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